Extrinsic and idiopathic vernal keratoconjunctivitis? Two cases with dissimilar immunopathology.
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چکیده
منابع مشابه
Extrinsic and idiopathic vernal keratoconjunctivitis? Two cases with dissimilar immunopathology.
Two clinically similar cases of vernal keratoconjunctivitis with dissimilar immunological data are reported. One patient had strikingly elevated IgE levels in both serum and tears, and his tear fluid contained specific IgE antibodies to a number of allergens. Conjunctival scrapings and peripheral blood samples showed marked eosinophilic reactions. The other patient showed normal values for tear...
متن کاملVernal keratoconjunctivitis
Vernal keratoconjunctivitis (VKC) is a chronic allergic conjunctivitis that is most often seen in young, males. Although most types of allergic conjunctivitis do not affect vision, VKC is unusual in that damage to the cornea from the condition can result in vision loss. Although it is typically seasonal, year-round symptoms can be seen, which can lead to uncertain diagnoses being made. Although...
متن کاملManagement of Vernal Keratoconjunctivitis
Vernal keratoconjunctivitis (VKC) is a relatively rare, chronic form of ocular allergy that can potentially cause severe visual complications. Affecting mainly children and young adults, it is an IgE- and T cell-mediated disease, leading to a chronic inflammation in which eosinophil, lymphocyte and structural cell activation are involved. Treatment of VKC requires a multiple approach that inclu...
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Vernal keratoconjunctivitis (VKC) is a bilateral, usually seasonally recurrent, allergic inflammation of the conjunctiva, characterised by limbal gelatinous hypertrophy and/or upper tarsal giant conjunctival papillae. Although rare in temperate regions, it represents an important cause of hospital referral in many parts of Africa and Asia. Clinical and immunohistochemical studies suggest that I...
متن کاملImmunological characteristics of patients with vernal keratoconjunctivitis.
PURPOSE Previously, we have reported that local excision and immunosuppressive treatment are useful in treating patients with very severe vernal keratoconjunctivitis (VKC). METHODS We measured serum levels of immunoglobulins, cytokines, and interleukin-2 receptors (IL-2R) and the concentration of IL-4 in tears of 10 patients with severe VKC, and made a comparison with data from 10 healthy con...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 1983
ISSN: 0007-1161
DOI: 10.1136/bjo.67.11.742